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@MannLabs

Mann Labs

MannLabs

We develop open-source software for MS-based proteomics, driven by teams at the Max Planck Institute of Biochemistry and the Centre for Proteomics Research (Copenhagen).

Our aim is to provide flexible and future-proof tools for proteomics that span the full data analysis pipeline - from efficient access to raw MS data, through peptide and protein identification and quantification, to biological interpretation and multi-omics integration. We pursue this through:

  • Open science: all software is released under permissive open-source licenses
  • Reproducibility and scientific quality: performant, well-tested, and well-documented methods
  • Accessibility: clear APIs, tutorials, and contribution guidelines
  • Community collaboration: tools designed to be extensible and interoperable

Learn more at https://alphapept.org or reach out on GitHub!

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  1. alphadia alphadia Public

    modular & open DIA search

    Jupyter Notebook 107 11

  2. alphapeptdeep alphapeptdeep Public

    Deep learning framework for proteomics

    Jupyter Notebook 149 26

  3. alphapept alphapept Public

    A modular, python-based framework for mass spectrometry. Powered by nbdev.

    HTML 187 35

  4. alphatims alphatims Public

    An open-source Python package for efficient accession and visualization of Bruker TimsTOF raw data from the Mann Labs at the Max Planck Institute of Biochemistry.

    Python 94 29

  5. alphaquant alphaquant Public

    An open-source Python package for accurate and sensitive peptide and protein quantification.

    Python 19 1

  6. alphapepttools alphapepttools Public

    Search- and quantification-engine agnostic biological interpretation of proteomics data

    Python 17 2

Repositories

Showing 10 of 56 repositories
  • scPortrait Public

    scPortrait is a scalable toolkit to generate single-cell representations from raw microscopy images

    MannLabs/scPortrait’s past year of commit activity
    Python 107 Apache-2.0 7 26 4 Updated Apr 13, 2026
  • alphadia Public

    modular & open DIA search

    MannLabs/alphadia’s past year of commit activity
    Jupyter Notebook 107 Apache-2.0 11 15 9 Updated Apr 13, 2026
  • alpharaw Public

    An open-source Python package to unify raw MS data accession and storage.

    MannLabs/alpharaw’s past year of commit activity
    Python 31 Apache-2.0 13 8 6 Updated Apr 13, 2026
  • alphapept-website Public

    Website for proteomics software tools developed in the MannLabs

    MannLabs/alphapept-website’s past year of commit activity
    HTML 0 0 1 (1 issue needs help) 1 Updated Apr 10, 2026
  • dvp-io Public

    Read/write functions to and from spatialdata for Deep Visual Proteomics

    MannLabs/dvp-io’s past year of commit activity
    Python 14 Apache-2.0 3 1 1 Updated Apr 10, 2026
  • alphakraken Public

    A fully automated data processing and analysis system for mass spectrometry experiments.

    MannLabs/alphakraken’s past year of commit activity
    Python 5 Apache-2.0 0 0 4 Updated Apr 9, 2026
  • alphapeptdeep Public

    Deep learning framework for proteomics

    MannLabs/alphapeptdeep’s past year of commit activity
    Jupyter Notebook 149 Apache-2.0 26 21 4 Updated Apr 8, 2026
  • alphapepttools Public

    Search- and quantification-engine agnostic biological interpretation of proteomics data

    MannLabs/alphapepttools’s past year of commit activity
    Python 17 Apache-2.0 2 1 7 Updated Apr 2, 2026
  • alphaquant Public

    An open-source Python package for accurate and sensitive peptide and protein quantification.

    MannLabs/alphaquant’s past year of commit activity
    Python 19 Apache-2.0 1 3 1 Updated Mar 27, 2026
  • pydiaid Public

    An open-source Python package for dia-PASEF methods with Automated Isolation Design (py_diAID) from the Mann Labs at the Max Planck Institute of Biochemistry.

    MannLabs/pydiaid’s past year of commit activity
    Jupyter Notebook 28 Apache-2.0 6 11 0 Updated Mar 19, 2026

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