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Updates for issue 90#105

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xiaoliz0 merged 41 commits into
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develop_issue90
Jun 2, 2026
Merged

Updates for issue 90#105
xiaoliz0 merged 41 commits into
mainfrom
develop_issue90

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@xiaoliz0

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Change filtering criteria:

  1. DO NOT filter out pathogenic germline variants.
  2. TERT always to report.

The gene with one of these 2 conditions will be reported with highest priority in PRONTO report.
These "rescued" variants should have a separate column in tables to verify this. Separate column "Filter rescued", values are "Yes" or empty.

Change filtering criteria: DO NOT filter out pathogenic germline variants. TERT always to report.
The genes with one of these 2 conditions will be reported with highest priority in PRONTO report.
These "rescued" variants should have a separate column (at the far right of the table) to verify this. Separate column "Filter rescued", values are "Yes" or empty.
@xiaoliz0 xiaoliz0 linked an issue Apr 22, 2026 that may be closed by this pull request
… should not appear in the tables appearing on the right of slides in report, but only printed this column in the summary table in slide 8.
@xiaoliz0 xiaoliz0 requested review from marrip and tonjegul April 30, 2026 11:09
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@marrip I just got further request for this issue. I updated in the issue 90. There will be some further new codes coming soon.

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marrip commented Apr 30, 2026

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@marrip I just got further request for this issue. I updated in the issue 90. There will be some further new codes coming soon.

ok, then I will wait with the review until you tell me to start ☺️

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xiaoliz0 commented May 4, 2026

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@marrip I just got further request for this issue. I updated in the issue 90. There will be some further new codes coming soon.

ok, then I will wait with the review until you tell me to start ☺️

The new commits implement the further request. Feel free to review the codes. @marrip :)

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marrip commented May 4, 2026

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will start latest tomorrow 🙂

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hey Xiaoli! I had a couple of questions and a suggestion. I am also working on a refactoring of some of the parts but need your input first ☺️ Will continue tomorrow.

Comment thread Script/PRONTO.py Outdated
Comment thread Script/PRONTO.py Outdated
Comment thread Script/PRONTO.py Outdated
Comment thread Script/PRONTO.py Outdated
Comment thread Script/PRONTO.py Outdated
@marrip

marrip commented May 6, 2026

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Looking at the remaining changes it seems that a lot of the fixes are to handle different column numbers of the combined tables, replacing tabs with linebreaks or vice versa and making data unique. I would suggest we rework this and use pandas instead which would make reading, filtering, combining and writing to file a lot easier. What do you think?

xiaoliz0 and others added 14 commits May 6, 2026 13:53
This is removed in main branch, not sure why it is existing here.

Co-authored-by: Martin Rippin <74295098+marrip@users.noreply.github.com>
…01-A08_small_variant_table_forQC.tsv

Remove old file due to some format issues.
Correct format issues.
…-D01-P01-A08_MTB_report.pptx

Remove old testing output.
Latest testing output report.
…01-A08_MTB_report.pptx to test_data/ous/test_files_for_PRONTO_newFunctions/output/IPD2225-D01-P01-A08_MTB_report.pptx

output folder added

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👍

@xiaoliz0 xiaoliz0 merged commit 6829ba9 into main Jun 2, 2026
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National request for data filter (big change)

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