From f333bec7f362ad47b1f646a0c3642d7e2bfd692a Mon Sep 17 00:00:00 2001
From: mite-bot <zdoucmm@gmail.com>
Date: Thu, 10 Sep 2026 16:02:25 +0200
Subject: [PATCH 1/2] Add submission UUID file

---
 .../9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json | 44 +++++++++++++++++++
 1 file changed, 44 insertions(+)
 create mode 100644 mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json

diff --git a/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json b/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json
new file mode 100644
index 00000000..ba4546ca
--- /dev/null
+++ b/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json
@@ -0,0 +1,44 @@
+{
+    "accession": "MITE9999999",
+    "status": "pending",
+    "changelog": [
+        {
+            "version": "1",
+            "date": "2026-09-10",
+            "contributors": [
+                "0009-0000-8651-1669"
+            ],
+            "reviewers": [
+                "BBBBBBBBBBBBBBBBBBBBBBBB"
+            ],
+            "comment": "New entry."
+        }
+    ],
+    "enzyme": {
+        "name": "AcOTAhal",
+        "databaseIds": {
+            "uniprot": "A0A2I7UGF8",
+            "genpept": ""
+        },
+        "references": [
+            "doi:"
+        ]
+    },
+    "reactions": [
+        {
+            "evidence": {
+                "evidenceCode": [],
+                "references": [
+                    "doi:"
+                ]
+            },
+            "reactions": [
+                {
+                    "products": [
+                        ""
+                    ]
+                }
+            ]
+        }
+    ]
+}
\ No newline at end of file

From 486d1881ec5998257b0d76b6a0c04e6ba1428e29 Mon Sep 17 00:00:00 2001
From: mite-bot <zdoucmm@gmail.com>
Date: Thu, 10 Sep 2026 16:30:53 +0200
Subject: [PATCH 2/2] Update submission

---
 .../9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json | 45 +++++++++++++------
 1 file changed, 32 insertions(+), 13 deletions(-)

diff --git a/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json b/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json
index ba4546ca..7eaf60aa 100644
--- a/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json
+++ b/mite_data/data/9d58006e-ad1e-11f1-b4b1-cf84655b59e7.json
@@ -1,6 +1,7 @@
 {
     "accession": "MITE9999999",
     "status": "pending",
+    "comment": "Halogenation of ochratoxin B in the ochratoxin A pathway. No flavin reductase was identified in this gene cluster.",
     "changelog": [
         {
             "version": "1",
@@ -16,29 +17,47 @@
     ],
     "enzyme": {
         "name": "AcOTAhal",
+        "description": "Flavin-dependent halogenase",
+        "references": [
+            "doi:10.1128/AEM.01209-16"
+        ],
         "databaseIds": {
             "uniprot": "A0A2I7UGF8",
-            "genpept": ""
+            "genpept": "AUS29481.1",
+            "mibig": "BGC0002605"
         },
-        "references": [
-            "doi:"
-        ]
+        "cofactors": {
+            "organic": [
+                "FAD",
+                "NAD"
+            ]
+        }
     },
     "reactions": [
         {
-            "evidence": {
-                "evidenceCode": [],
-                "references": [
-                    "doi:"
-                ]
-            },
+            "tailoring": [
+                "Halogenation"
+            ],
+            "description": "Single chlorination of ochratoxin B",
+            "reactionSMARTS": "[#6:1]\\[#6@:2]1-[#8:12]-[#6:10](=[#8:11])-[#6:9]2:[#6:4](:[#6:5]:[#6:6]:[#6:7](-[#6:14](-[#7:16]/[#6@:17](-[#6:25](-[#8:27])=[#8:26])-[#6:18]-[#6:19]3:[#6:24]:[#6:23]:[#6:22]:[#6:21]:[#6:20]:3)=[#8:15]):[#6:8]:2-[#8:13])-[#6:3]-1>>[#6:1]\\[#6@:2]1-[#8:12]-[#6:10](=[#8:11])-[#6:9]2:[#6:4](:[#6:5](-[Cl]):[#6:6]:[#6:7](-[#6:14](-[#7:16]/[#6@:17](-[#6:25](-[#8:27])=[#8:26])-[#6:18]-[#6:19]3:[#6:20]:[#6:21]:[#6:22]:[#6:23]:[#6:24]:3)=[#8:15]):[#6:8]:2-[#8:13])-[#6:3]-1",
             "reactions": [
                 {
+                    "substrate": "C[C@@H]1Cc2ccc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1",
                     "products": [
-                        ""
-                    ]
+                        "C[C@@H]1Cc2c(Cl)cc(C(=O)N[C@@H](Cc3ccccc3)C(=O)O)c(O)c2C(=O)O1"
+                    ],
+                    "isIntermediate": false,
+                    "description": "Chlorination of ochratoxin B to ochratoxin A"
                 }
-            ]
+            ],
+            "evidence": {
+                "evidenceCode": [
+                    "Knock-out studies"
+                ],
+                "references": [
+                    "doi:10.1128/AEM.01209-16"
+                ]
+            }
         }
     ]
 }
\ No newline at end of file