diff --git a/CHANGELOG.md b/CHANGELOG.md index 983757d9..1c282157 100644 --- a/CHANGELOG.md +++ b/CHANGELOG.md @@ -14,6 +14,10 @@ selecting between the `wiggle150` and `folmsbee` reference datasets, and refactor `run_model` to run a single batched inference call across all conformers. +- Record JAX peak device memory (`peak_bytes_in_use`) per structure in the + scaling benchmark. Surfaced as `ScalingStructureResult.peak_memory_bytes` + and as a "Peak memory vs system size" chart on the scaling UI page. Falls + through to `None` on backends that do not expose `memory_stats()`. ## Release 0.1.2 diff --git a/docs/source/benchmarks/general/scaling.rst b/docs/source/benchmarks/general/scaling.rst index 80ebfc41..2b007f97 100644 --- a/docs/source/benchmarks/general/scaling.rst +++ b/docs/source/benchmarks/general/scaling.rst @@ -26,23 +26,16 @@ optimization strategies for large-scale simulations. Dataset ------- -The scaling dataset is composed of a series of protein structures, RNA fragments, -peptides and small-molecules experimental structures taken from the `PDB `_ databank. -They have the following ids: - -* 1JRS -* 1AY3 -* 1UAO -* 1P79 -* 5KGZ -* 7CI3 -* 1AB7 -* 1BIP -* 1A5E -* 1A7M -* 2BQV -* 1J7H -* 1VSQ +The scaling dataset is a size-stratified set of protein chains taken from the +`PDB `_. Chains were sourced from a PISCES cull list +(non-redundant at 25% sequence identity, resolution ≤ 2.0 Å, no chain breaks) +and a curated small-protein list, screened to charge-neutral sequences at pH 7: + +* **2JOF** chain A — Trp-cage TC10b mini-protein (284 atoms) +* **1R0R** chain I — turkey ovomucoid third domain (OMTKY3) (748 atoms) +* **3TXS** chain A — bacteriophage 44RR small terminase gp16 (1513 atoms) +* **4QMD** chain A — human envoplakin plakin-repeat domain (3018 atoms) +* **6U1V** chain A — TcsD acyl-CoA dehydrogenase from FK506 biosynthesis (5964 atoms) Interpretation -------------- diff --git a/src/mlipaudit/benchmarks/scaling/scaling.py b/src/mlipaudit/benchmarks/scaling/scaling.py index c0bc0d7d..09d4d090 100644 --- a/src/mlipaudit/benchmarks/scaling/scaling.py +++ b/src/mlipaudit/benchmarks/scaling/scaling.py @@ -18,9 +18,16 @@ from pathlib import Path from typing import Any +import jax from ase.io import read as ase_read from mlip.simulation import SimulationState -from pydantic import BaseModel, ConfigDict, NonNegativeFloat, PositiveInt +from pydantic import ( + BaseModel, + ConfigDict, + NonNegativeFloat, + NonNegativeInt, + PositiveInt, +) from mlipaudit.benchmark import ( DEFAULT_CHARGE, @@ -47,31 +54,26 @@ } NUM_DEV_SYSTEMS = 2 -# Total charge per structure (keyed by xyz file stem). The structure set is -# discovered at runtime from the data directory; any structure not listed here -# falls back to a neutral charge of 0. All systems are treated as closed-shell -# singlets (spin multiplicity = 1). Values are sequence-based estimates from -# the FASTA at pH 7 (K+R counted +1, D+E counted -1, HIS neutral, termini -# cancel per chain); cross-checked against the observed electron parity. -STRUCTURE_CHARGES: dict[str, float] = { - "71_1jrs_leupeptin": 1.0, - "121_1ay3": -1.0, - "138_1uao_chignolin": -2.0, - "168_1p79_RNA": -4.0, - "634_5kgz": -1.0, - "1061_7ci3": -1.0, - "1432_1ab7": -6.0, - "1818_1bip": 2.0, - "2301_1a5e": -5.0, - "2803_1a7m": 7.0, - "3346_2bqv": 2.0, - "5990_1j7h_atoms_removed": -3.0, - "6713_1vsq": -7.0, -} - logger = logging.getLogger("mlipaudit") +def _peak_device_bytes() -> int | None: + """Return the JAX backend's peak device memory in bytes since process start. + + Reads `peak_bytes_in_use` from the default device's `memory_stats()`. Returns + `None` when the active backend does not report memory stats (e.g. the JAX CPU + backend on some platforms), so callers can fall through without special-casing. + """ + try: + stats = jax.devices()[0].memory_stats() + except Exception: + return None + if not stats: + return None + peak = stats.get("peak_bytes_in_use") + return int(peak) if peak is not None else None + + class ScalingModelOutput(ModelOutput): """Model output for the scaling benchmark. @@ -84,11 +86,18 @@ class ScalingModelOutput(ModelOutput): for each corresponding structure, excluding the first episode to ignore the compilation time. None if the simulation failed. + peak_memory_bytes: A list of peak device-memory readings (in bytes) taken + after each structure's simulation. The reading is the cumulative + JAX `peak_bytes_in_use` since process start, so for the size-sorted + structure sequence the value also bounds the per-system peak from + above. `None` if the simulation failed before producing a reading, + or if the backend does not expose memory stats. """ structure_names: list[str] simulation_states: list[SimulationState | None] average_episode_times: list[float | None] + peak_memory_bytes: list[int | None] model_config = ConfigDict(arbitrary_types_allowed=True) @@ -105,6 +114,12 @@ class ScalingStructureResult(BaseModel): excluding the first episode to ignore the compilation time. average_step_time: The average step time of the simulation, excluding the first episode to ignore the compilation time. + peak_memory_bytes: The JAX backend's `peak_bytes_in_use` after the + simulation completed (or after it failed, when a reading was still + obtainable). Cumulative since process start, so plotting against + `num_atoms` for the size-sorted structure list traces the + high-water mark as a function of system size. `None` when the + active JAX backend does not expose memory stats. failed: Whether the simulation failed. """ @@ -114,6 +129,7 @@ class ScalingStructureResult(BaseModel): num_episodes: PositiveInt average_episode_time: NonNegativeFloat | None = None average_step_time: NonNegativeFloat | None = None + peak_memory_bytes: NonNegativeInt | None = None failed: bool = False @@ -205,7 +221,7 @@ class ScalingBenchmark(Benchmark): result_class = ScalingResult model_output_class = ScalingModelOutput - required_elements = {"N", "H", "O", "S", "P", "C"} + required_elements = {"N", "H", "O", "S", "C"} def run_model(self) -> None: """Runs a short MD simulation for each structure, timing each @@ -214,15 +230,14 @@ def run_model(self) -> None: """ simulation_states: list[SimulationState | None] = [] average_episode_times: list[float | None] = [] + peak_memory_bytes: list[int | None] = [] for structure_name in self._structure_names: try: timer = Timer() atoms = ase_read( self.data_input_dir / self.name / f"{structure_name}.xyz" ) - atoms.info["charge"] = float( - STRUCTURE_CHARGES.get(structure_name, DEFAULT_CHARGE) - ) + atoms.info["charge"] = DEFAULT_CHARGE atoms.info["spin"] = DEFAULT_SPIN md_engine = get_simulation_engine( atoms=atoms, @@ -242,11 +257,14 @@ def run_model(self) -> None: ) simulation_states.append(None) average_episode_times.append(None) + finally: + peak_memory_bytes.append(_peak_device_bytes()) self.model_output = ScalingModelOutput( structure_names=self._structure_names, simulation_states=simulation_states, average_episode_times=average_episode_times, + peak_memory_bytes=peak_memory_bytes, ) def analyze(self) -> ScalingResult: @@ -263,6 +281,7 @@ def analyze(self) -> ScalingResult: structure_results = [] for i, structure_name in enumerate(self._structure_names): + peak_memory = self.model_output.peak_memory_bytes[i] if self.model_output.average_episode_times[i] is None: structure_results.append( ScalingStructureResult( @@ -270,6 +289,7 @@ def analyze(self) -> ScalingResult: num_atoms=get_molecule_size_from_name(structure_name), num_steps=self._md_kwargs["num_steps"], num_episodes=self._md_kwargs["num_episodes"], + peak_memory_bytes=peak_memory, failed=True, ) ) @@ -288,6 +308,7 @@ def analyze(self) -> ScalingResult: num_episodes=self._md_kwargs["num_episodes"], average_episode_time=average_episode_time, average_step_time=average_step_time, + peak_memory_bytes=peak_memory, ) ) diff --git a/src/mlipaudit/ui/scaling.py b/src/mlipaudit/ui/scaling.py index f431b3c9..acc24322 100644 --- a/src/mlipaudit/ui/scaling.py +++ b/src/mlipaudit/ui/scaling.py @@ -41,6 +41,11 @@ def _process_data_into_dataframe( if structure_result.failed: continue + peak_memory_mb = ( + structure_result.peak_memory_bytes / (1024**2) + if structure_result.peak_memory_bytes is not None + else None + ) df_data.append({ "Model name": model_name, "Structure": structure_result.structure_name, @@ -49,6 +54,7 @@ def _process_data_into_dataframe( "Num steps": structure_result.num_steps, "Num episodes": structure_result.num_episodes, "Average step time (s)": structure_result.average_step_time, + "Peak memory (MB)": peak_memory_mb, }) return pd.DataFrame(df_data) @@ -100,6 +106,40 @@ def plot_all_models_performance(df: pd.DataFrame) -> alt.Chart: return chart +def plot_all_models_memory(df: pd.DataFrame) -> alt.Chart | None: + """Plot peak device memory vs system size for all models together. + + Args: + df: The dataframe containing per-structure rows, including a + "Peak memory (MB)" column. Rows where the column is null are + dropped (the active JAX backend does not expose memory stats). + + Returns: + The Altair chart, or None if no rows have memory data. + """ + df_mem = df.dropna(subset=["Peak memory (MB)"]) + if df_mem.empty: + return None + + base = alt.Chart(df_mem).encode( + x=alt.X("Num atoms:Q", title="System size (number of atoms)"), + y=alt.Y("Peak memory (MB):Q", title="Peak device memory (MB)"), + color=alt.Color( + "Model name:N", title="Model", legend=alt.Legend(title="Model") + ), + tooltip=[ + alt.Tooltip("Model name:N", title="Model"), + alt.Tooltip("Structure:N", title="Structure"), + alt.Tooltip("Num atoms:Q", title="Number of atoms"), + alt.Tooltip("Peak memory (MB):Q", title="Peak memory (MB)", format=".1f"), + ], + ) + + chart = base.mark_point(size=60, opacity=0.7).properties(width=800, height=500) + st.altair_chart(chart, use_container_width=True) + return chart + + def scaling_page( data_func: Callable[[], BenchmarkResultForMultipleModels], ) -> None: @@ -151,6 +191,14 @@ def scaling_page( chart = plot_all_models_performance(df) # noqa: F841 + st.markdown("## Peak device memory vs system size") + mem_chart = plot_all_models_memory(df) # noqa: F841 + if mem_chart is None: + st.markdown( + "*No memory readings available — the active JAX backend does not " + "expose `memory_stats()` (e.g. CPU runs).*" + ) + class ScalingPageWrapper(UIPageWrapper): """Page wrapper for scaling benchmark.""" diff --git a/tests/data/scaling/121_1ay3.xyz b/tests/data/scaling/121_1ay3.xyz deleted file mode 100644 index f3d026cb..00000000 --- a/tests/data/scaling/121_1ay3.xyz +++ /dev/null @@ -1,3289 +0,0 @@ -121 -final_systems_pdb/1ay3.pdb -C -0.61000 0.03700 3.17800 -O -1.13500 0.76300 4.02900 -O -0.95300 -0.15100 2.00700 -C 0.68300 -0.72900 3.64000 -N 1.76700 0.23000 3.35200 -C 0.82200 -2.14400 2.94400 -C 1.58600 -2.08200 1.61200 -C 1.47800 -3.23700 3.80800 -O 2.80000 -1.87000 1.59300 -H 0.65100 -0.86500 4.73200 -H 2.29300 0.07000 2.50400 -H -0.21100 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2.05900 -0.49400 -N 2.58700 2.72600 -1.21800 -C 4.04000 2.50800 -1.30900 -C 4.59900 3.97200 -1.34100 -O 4.99700 4.44400 -0.27300 -C 4.58300 1.52500 -0.25000 -C 4.37900 1.81000 1.25100 -C 5.06100 0.75000 2.16800 -O 5.81600 -0.08000 1.67000 -H 2.26100 3.17500 -0.37900 -H 4.23600 2.06200 -2.30000 -H 4.14300 0.53200 -0.45800 -H 5.66300 1.41100 -0.42100 -H 4.81900 2.78100 1.53000 -H 3.30200 1.86900 1.48500 -N 4.79500 0.78500 3.56200 -C 5.31600 -0.35000 4.33400 -C 3.79100 1.63300 4.12200 -C 2.43400 1.04300 4.43200 -O 1.89700 1.23500 5.51700 -C 4.03900 2.94900 4.37300 -C 5.31700 3.72400 4.16900 -H 5.04500 -0.21100 5.39100 -H 6.41400 -0.40900 4.26800 -H 4.88400 -1.30100 3.98600 -H 3.25600 3.59100 4.78900 -H 6.14700 3.11800 3.78200 -H 5.64500 4.16400 5.12500 -H 5.14700 4.54900 3.45700 -H -0.59291 1.29326 4.61959 -H 4.63261 4.51693 -2.21675 -119 -final_systems_pdb/1ay3.pdb -C -0.53000 0.24900 3.00400 -O -0.97900 1.12700 3.75000 -O -0.89100 -0.04900 1.86200 -C 0.67400 -0.57800 3.58900 -N 1.84700 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6.18800 -6.31000 -1.84700 -H 4.84200 -8.75200 0.56100 -H 6.28000 -8.18200 -0.18900 -N 0.22800 -0.09900 -1.24400 -C 0.21000 2.32700 -1.82400 -C 1.70400 2.19400 -2.15100 -O 2.06800 1.66100 -3.20100 -C -0.49200 0.96000 -1.96300 -C -0.36400 3.42600 -2.74200 -C -5.40600 0.35000 -2.29500 -C -4.41100 0.96100 -1.61000 -C -3.04700 0.86800 -2.21900 -C -1.92900 1.06800 -1.49000 -C -6.50400 -1.70500 -0.31500 -C -7.18800 -1.26700 -1.65000 -C -6.87800 0.23000 -1.93900 -C -8.93100 -1.25000 3.27200 -C -8.24900 -0.15000 2.74200 -C -7.47100 -0.29600 1.59300 -C -7.35500 -1.52700 0.93900 -C -8.03400 -2.62000 1.49200 -C -8.81600 -2.49200 2.63900 -O -8.60500 -1.44300 -1.62300 -C -9.00200 -2.75900 -1.95800 -C -7.71400 0.89200 -3.06200 -C -4.71100 1.68200 -0.30500 -H 0.76000 0.17700 -0.43400 -H 0.09000 2.67400 -0.78100 -H -0.47400 0.68600 -3.02800 -H -1.41900 3.62400 -2.49500 -H 0.19600 4.36600 -2.61500 -H -0.30900 3.13200 -3.80200 -H -5.16400 -0.18700 -3.21800 -H -2.90100 0.59800 -3.26900 -H -2.01800 1.31800 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2.53500 -1.31100 -C 4.62100 3.99400 -1.33200 -O 4.58000 4.54000 -2.44300 -C 4.58500 1.54100 -0.25800 -C 4.37900 1.81600 1.24500 -C 5.05400 0.74800 2.15600 -O 5.80600 -0.08200 1.65700 -H 2.27900 3.21200 -0.38000 -H 4.24600 2.09400 -2.30400 -H 4.13800 0.55300 -0.47300 -H 5.66400 1.41800 -0.42600 -H 4.82400 2.78300 1.53200 -H 3.30200 1.87800 1.47700 -N 4.78400 0.77700 3.54900 -C 5.29600 -0.36500 4.31800 -C 3.78200 1.62700 4.11000 -C 2.42500 1.04000 4.42000 -O 1.89400 1.22600 5.51000 -C 4.03500 2.94100 4.37100 -C 5.31700 3.71200 4.17500 -H 5.01800 -0.23100 5.37400 -H 6.39300 -0.42700 4.25800 -H 4.86300 -1.31200 3.96100 -H 3.25500 3.58200 4.79100 -H 6.14300 3.10800 3.77800 -H 5.64900 4.13600 5.13800 -H 5.14900 4.54900 3.47700 -H -0.61183 1.26058 4.63151 -H 4.05157 4.58592 -0.64623 -H 5.65405 3.92453 -1.06203 -H 3.65667 4.62378 -2.72822 -121 -final_systems_pdb/1ay3.pdb -C -0.58100 0.08500 3.11400 -O -1.08300 0.87200 3.92400 -O -0.93100 -0.15700 1.95500 -C 0.68700 -0.69400 3.62700 -N 1.79700 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+H 24.772184 6.875009 31.939971 +H 24.859133 6.138754 30.492015 +H 23.643825 5.776887 31.517475 +N 25.321355 -1.177149 33.059978 +H 24.640255 -0.911604 33.756895 +C 25.007031 -2.312429 32.184019 +H 25.862792 -2.987509 32.177780 +C 24.761624 -1.880364 30.718565 +O 24.058297 -0.867740 30.482895 +C 23.802366 -3.084304 32.736955 +H 23.597121 -3.913193 32.059522 +H 22.929568 -2.431898 32.710712 +S 23.957899 -3.763510 34.409826 +O 25.255694 -2.576020 29.800031 diff --git a/tests/scaling/test_scaling.py b/tests/scaling/test_scaling.py index f576f977..65b75cb9 100644 --- a/tests/scaling/test_scaling.py +++ b/tests/scaling/test_scaling.py @@ -59,36 +59,39 @@ def test_full_run_with_mocked_engine(scaling_benchmark, mock_jaxmd_simulation_en # We skip running the model due to complexity in running the # Timer with a mocked simulation engine. num_frames = 10 - positions_1jrs = np.tile( - np.ones((71, 3)), + positions_2jof = np.tile( + np.ones((284, 3)), reps=(num_frames, 1, 1), ) - positions_1ay3 = np.tile( - np.ones((121, 3)), + positions_1r0r = np.tile( + np.ones((748, 3)), reps=(num_frames, 1, 1), ) benchmark.model_output = ScalingModelOutput( - structure_names=["71_1jrs_leupeptin", "121_1ay3"], + structure_names=["284_2jof_A", "748_1r0r_I"], simulation_states=[ - SimulationState(positions=positions_1jrs), - SimulationState(positions=positions_1ay3), + SimulationState(positions=positions_2jof), + SimulationState(positions=positions_1r0r), ], average_episode_times=[0.05, 0.1], + peak_memory_bytes=[1_048_576, 2_097_152], ) result = benchmark.analyze() assert type(result) is ScalingResult assert len(result.structures) == 2 - assert result.structures[0].structure_name == "71_1jrs_leupeptin" - assert result.structures[0].num_atoms == 71 + assert result.structures[0].structure_name == "284_2jof_A" + assert result.structures[0].num_atoms == 284 assert result.structures[0].num_steps == 10 assert result.structures[0].num_episodes == 10 assert result.structures[0].average_episode_time == 0.05 assert result.structures[0].average_step_time == 0.05 + assert result.structures[0].peak_memory_bytes == 1_048_576 assert result.structures[1].average_episode_time == 0.1 + assert result.structures[1].peak_memory_bytes == 2_097_152 def test_analyze_raises_error_if_run_first(scaling_benchmark):