diff --git a/requirements.txt b/requirements.txt
index 575863f..0b498e0 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -33,5 +33,5 @@ rich==13.7.1
 rootutils==1.0.7
 scanpy==1.10.0
 scipy==1.13.1
-setuptools==68.2.0
+setuptools==74.0.0
 tqdm==4.66.2