diff --git a/README.md b/README.md
index 769fae52a9..9106c3a088 100644
--- a/README.md
+++ b/README.md
@@ -397,18 +397,24 @@ uv sync --extra cu13
 uv run python -c "import physicsnemo; print('PhysicsNeMo version:', physicsnemo.__version__)"
 ```
 
-To install with optional feature extras (e.g., `nn-extras`):
+To install with optional feature extras (e.g., `model-extras`):
 
 ```Bash
-uv sync --extra cu13 --extra nn-extras
+uv sync --extra cu13 --extra model-extras
 ```
 
 For a CUDA 12 environment, replace `cu13` with `cu12`:
 
 ```Bash
-uv sync --extra cu12 --extra nn-extras
+uv sync --extra cu12 --extra model-extras
 ```
 
+**Note:** Extras such as `gnns`, `nn-extras`, and `transformer-engine`
+ pull in packages that either ship only source distributions or require
+ wheels built for a specific PyTorch and CUDA version. These should be
+ installed with `--no-build-isolation`,
+ e.g. `uv sync --extra cu13 --extra nn-extras --no-build-isolation`.
+
 ### NVCR Container
 
 The recommended PhysicsNeMo Docker image can be pulled from the